二に茂しげる铁甲酸さん

二に茂しげる铁甲酸さん
识别
CAS号ごう	1271-42-7
性せい质
化学かがく式しき	C11H10FeO2
摩ま尔质量りょう	230.04 g·mol−1
熔点	194—197 °C（467—470 K）（分解ぶんかい）; 205 °C（478 K）（分解ぶんかい）
pKa	6.78
	若わか非ひ注ちゅう明あかり，所有しょゆう数すう据すえ均ひとし出自しゅつじ标准状じょう态（25 ℃，100 kPa）下した。

二に茂しげる铁甲酸さん是ぜ一いち种有ゆう机つくえ化合かごう物ぶつ，化学かがく式しき为C₁₁H₁₀FeO₂。

合成ごうせい

将はた正せい丁ちょう基はじめ锂在ざい搅拌下か滴しずく加か至いたり二に茂しげる铁的てき无水乙おつ醚溶液ようえき中ちゅう，发生锂化反はん应（而C-H酸性さんせい更さら弱じゃく的てき苯无明あかり显反应）；待まち反はん应结束たば后きさき将しょう混合こんごう物ぶつ加入かにゅう至いたり干ひ冰-乙おつ醚的混合こんごう物ぶつ中ちゅう搅拌，干ひ冰消失しょうしつ后きさき加入かにゅう冷水れいすい，分ふん离出水しゅっすい相しょう后きさき加か6 N盐酸酸化さんか，沉淀出で产物二に茂しげる铁甲酸さん，副ふく产物二茂铁二甲酸占30%。它们通どおり过在乙おつ酸さん中ちゅう结晶分ぶん离提纯。^[3]

性せい质

二茂铁甲酸具有弱酸性，比ひ苯甲酸さん弱じゃく大だい约三さん倍ばい。^[3]它可以和碱反应，生成せいせい二茂铁甲酸盐；^[4]草くさ酰氯反はん应，得とく到いた二茂铁甲酰氯。^[5]

参考さんこう文献ぶんけん

^ Harold Shechter, John F. Helling. Ferrocenyl and 1,1'-Ferrocenylene Grignard Reagents 1a. The Journal of Organic Chemistry. 1961-04, 26 (4): 1034–1037 [2020-12-24]. ISSN 0022-3263. doi:10.1021/jo01063a013 （英えい语）.
^ Andrei S. Batsanov, Damien Hérault, Judith A. K. Howard, Leonard G. F. Patrick, Michael R. Probert, Andrew Whiting. Synthesis and Structure of Planar Chiral, Bifunctional Aminoboronic Acid Ferrocene Derivatives. Organometallics. 2007-04, 26 (9): 2414–2419 [2020-12-24]. ISSN 0276-7333. doi:10.1021/om070038l （英えい语）.
^ ^3.0 ^3.1 ^3.2 Robert A. Benkeser, Donald Goggin, Gene Schroll. A Route to Monosubstituted Ferrocene Compounds. Journal of the American Chemical Society. 1954-08, 76 (15): 4025–4026 [2020-12-24]. ISSN 0002-7863. doi:10.1021/ja01644a047 （英えい语）.
^ Neto, Alberto Federman; Miller, Joseph; Andrade, Vânia Faria de; Fujimoto, Susana Yumi; Afonso, Márcia Maísa de Freitas; Archanjo, Fernando Costa; Darin, Vítor André; Silva, Márcio Luís Andrade e; Borges, Áurea Donizete Lanchote; Ponte, Gino Del. New Synthesis of Ferrocene Monocarboxylic Acid and Systematic Studies on the Preparation of Related Key-Intermediates. Zeitschrift für anorganische und allgemeine Chemie. 2002, 628 (1): 209–216. ISSN 0044-2313. doi:10.1002/1521-3749(200201)628:1<209::AID-ZAAC209>3.0.CO;2-C （德とく语）.
^ Muhammad Saleem, Haojie Yu, Li Wang, Zain-ul-Abdin, Hamad Khalid, Muhammad Akram, Nasir M. Abbasi, Yongsheng Chen. Study on synthesis of ferrocene-based boronic acid derivatives and their saccharides sensing properties. Journal of Electroanalytical Chemistry. 2016-02, 763: 71–78 [2020-12-24]. doi:10.1016/j.jelechem.2015.12.028. （原始げんし内容ないよう存そん档于2018-06-17）（英えい语）.

[1] Harold Shechter, John F. Helling. Ferrocenyl and 1,1'-Ferrocenylene Grignard Reagents 1a. The Journal of Organic Chemistry. 1961-04, 26 (4): 1034–1037 [2020-12-24]. ISSN 0022-3263. doi:10.1021/jo01063a013 （英えい语）.

[2] Andrei S. Batsanov, Damien Hérault, Judith A. K. Howard, Leonard G. F. Patrick, Michael R. Probert, Andrew Whiting. Synthesis and Structure of Planar Chiral, Bifunctional Aminoboronic Acid Ferrocene Derivatives. Organometallics. 2007-04, 26 (9): 2414–2419 [2020-12-24]. ISSN 0276-7333. doi:10.1021/om070038l （英えい语）.

[Robert-3] 3.0 ^3.1 ^3.2 Robert A. Benkeser, Donald Goggin, Gene Schroll. A Route to Monosubstituted Ferrocene Compounds. Journal of the American Chemical Society. 1954-08, 76 (15): 4025–4026 [2020-12-24]. ISSN 0002-7863. doi:10.1021/ja01644a047 （英えい语）.

[4] Neto, Alberto Federman; Miller, Joseph; Andrade, Vânia Faria de; Fujimoto, Susana Yumi; Afonso, Márcia Maísa de Freitas; Archanjo, Fernando Costa; Darin, Vítor André; Silva, Márcio Luís Andrade e; Borges, Áurea Donizete Lanchote; Ponte, Gino Del. New Synthesis of Ferrocene Monocarboxylic Acid and Systematic Studies on the Preparation of Related Key-Intermediates. Zeitschrift für anorganische und allgemeine Chemie. 2002, 628 (1): 209–216. ISSN 0044-2313. doi:10.1002/1521-3749(200201)628:1<209::AID-ZAAC209>3.0.CO;2-C （德とく语）.

[5] Muhammad Saleem, Haojie Yu, Li Wang, Zain-ul-Abdin, Hamad Khalid, Muhammad Akram, Nasir M. Abbasi, Yongsheng Chen. Study on synthesis of ferrocene-based boronic acid derivatives and their saccharides sensing properties. Journal of Electroanalytical Chemistry. 2016-02, 763: 71–78 [2020-12-24]. doi:10.1016/j.jelechem.2015.12.028. （原始げんし内容ないよう存そん档于2018-06-17）（英えい语）.

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