CXCL9

CXCL9
識別しきべつ號ごう
别名	CXCL9；, CMK, Humig, MIG, SCYB9, crg-10, C-X-C motif chemokine ligand 9
外部がいぶID	OMIM：601704 MGI：1352449 HomoloGene：1813 GeneCards：CXCL9
基もと因いん位置いち（人ひと类）
染色せんしょく体たい	4號ごう染色せんしょく體たい
终止	76,007,509 bp
基もと因いん位置いち（小しょう鼠ねずみ）
染色せんしょく体たい	小しょう鼠ねずみ5号ごう染色せんしょく体たい
终止	92,475,938 bp
RNA表ひょう达模も式しき
	查阅更さら多た表ひょう达数据すえ
基もと因いん本體ほんたい
分子ぶんし功こう能のう	• 細胞さいぼう因子いんし活性かっせい; • CXCR3 chemokine receptor binding; • chemokine activity; • 血ち浆蛋白しろ结合;
細胞さいぼう組ぐみ分ぶん	• 細胞さいぼう外がい區域くいき; • external side of plasma membrane; • 細胞さいぼう外がい空間くうかん; • 胞內;
生物せいぶつ學がく過程かてい	• G protein-coupled receptor signaling pathway; • chemokine-mediated signaling pathway; • cell-cell signaling; • positive regulation of release of sequestered calcium ion into cytosol; • positive regulation of cAMP-mediated signaling; • 趨化性せい; • positive regulation of leukocyte chemotaxis; • cellular defense response; • positive regulation of myoblast fusion; • response to lipopolysaccharide; • regulation of cell population proliferation; • positive regulation of myoblast differentiation; • defense response to virus; • 免疫めんえき反はん应; • 訊息傳でん遞; • defense response; • inflammatory response; • T cell chemotaxis; • antimicrobial humoral immune response mediated by antimicrobial peptide; • regulation of signaling receptor activity; • adenylate cyclase-activating G protein-coupled receptor signaling pathway; • response to bacterium; • neutrophil chemotaxis; • leukocyte chemotaxis; • cellular response to lipopolysaccharide;
	Sources:Amigo / QuickGO
直系ちょっけい同どう源みなもと
	4283
	17329
	ENSG00000138755
	ENSMUSG00000029417
	Q07325
	P18340
	NM_002416
	NM_008599
	NP_002407
	NP_032625
	維基數すう據よりどころ
檢視けんし/編輯へんしゅう人類じんるい	檢視けんし/編輯へんしゅう小しょう鼠ねずみ

CXCL9（英語えいご：Chemokine (C-X-C motif) ligand 9）是ぜ一いち小しょう分子ぶんし的てき细胞因子いんし属ぞく于CXC趋化因子いんし家族かぞく，又また被ひ称しょう作さく“干ひ扰素伽とぎ玛诱导的单核细胞因子いんし”（Monokine induced by gamma interferon, MIG）^[5] 。CXCL9是ぜT细胞趋化因子いんし^[5] 。干ひ扰素伽とぎ玛诱导CXCL9的てき表ひょう达。人ひと类的CXCL9与あずかCXCL10，CXCL11的てき基もと因いん相しょう邻聚集しゅう在ざい第だい四よん染色せんしょく体たい上じょう^[6] 。CXCL9，CXCL10, CXCL11结合趋化因子いんし受体CXCR3而起其细胞趋化か作用さよう^[7]^[8] 。

参まいり见

参考さんこう文献ぶんけん

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000138755 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000029417 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^5.0 ^5.1 Liao F, Rabin RL, Yannelli JR, Koniaris LG, Vanguri P, Farber JM. Human Mig chemokine: biochemical and functional characterization. J Exp Med. 1995 Nov 1;182(5):1301-14.
^ Lee HH, Farber JM. Localization of the gene for the human MIG cytokine on chromosome 4q21 adjacent to INP10 reveals a chemokine "mini-cluster". Cytogenet Cell Genet. 1996;74(4):255-8.
^ Loetscher M, Gerber B, Loetscher P, Jones SA, Piali L, Clark-Lewis I, Baggiolini M, Moser B. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med. 1996 Sep 1;184(3):963-9.
^ Weng Y, Siciliano SJ, Waldburger KE, Sirotina-Meisher A, Staruch MJ, Daugherty BL, Gould SL, Springer MS, DeMartino JA. Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors. J Biol Chem. 1998 Jul 17;273(29):18288-91.

外部がいぶ链接

Charo IF, Ransohoff RM. The many roles of chemokines and chemokine receptors in inflammation. N Engl J Med. 2006 Feb 9;354(6):610-21.（页面存そん档备份，存そん于互联网档案あん馆）

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000138755 - Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000029417 - Ensembl, May 2017

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[liao-5] 5.0 ^5.1 Liao F, Rabin RL, Yannelli JR, Koniaris LG, Vanguri P, Farber JM. Human Mig chemokine: biochemical and functional characterization. J Exp Med. 1995 Nov 1;182(5):1301-14.

[6] Lee HH, Farber JM. Localization of the gene for the human MIG cytokine on chromosome 4q21 adjacent to INP10 reveals a chemokine "mini-cluster". Cytogenet Cell Genet. 1996;74(4):255-8.

[7] Loetscher M, Gerber B, Loetscher P, Jones SA, Piali L, Clark-Lewis I, Baggiolini M, Moser B. Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes. J Exp Med. 1996 Sep 1;184(3):963-9.

[8] Weng Y, Siciliano SJ, Waldburger KE, Sirotina-Meisher A, Staruch MJ, Daugherty BL, Gould SL, Springer MS, DeMartino JA. Binding and functional properties of recombinant and endogenous CXCR3 chemokine receptors. J Biol Chem. 1998 Jul 17;273(29):18288-91.

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