MYO1A

MYO1A
識別しきべつ號ごう
别名	MYO1A；, BBMI, DFNA48, MIHC, MYHL, myosin IA
外部がいぶID	OMIM：601478 MGI：107732 HomoloGene：21113 GeneCards：MYO1A
基もと因いん位置いち（人ひと类）
染色せんしょく体たい	12號ごう染色せんしょく體たい
终止	57,051,198 bp
基もと因いん位置いち（小しょう鼠ねずみ）
染色せんしょく体たい	小しょう鼠ねずみ10号ごう染色せんしょく体たい
终止	127,556,809 bp
RNA表ひょう达模も式しき
	查阅更さら多た表ひょう达数据すえ
基もと因いん本體ほんたい
分子ぶんし功こう能のう	• 核かく苷酸結合けつごう; • actin binding; • actin filament binding; • cytoskeletal motor activity; • calmodulin binding; • ATP結合けつごう; • microtubule motor activity; • microtubule binding;
細胞さいぼう組ぐみ分ぶん	• filamentous actin; • 刷すり狀じょう緣えん; • 細胞さいぼう質しつ; • cortical actin cytoskeleton; • 微ほろ绒毛; • apical plasma membrane; • basal plasma membrane; • plasma membrane raft; • myosin complex; • basolateral plasma membrane; • lateral plasma membrane;
生物せいぶつ學がく過程かてい	• Q14865145; • microvillus assembly; • cell projection organization; • vesicle localization; • microtubule-based movement;
	Sources:Amigo / QuickGO
直系ちょっけい同どう源みなもと
	4640
	432516
	ENSG00000166866
	ENSMUSG00000025401
	Q9UBC5
	O88329
	NM_001256041; NM_005379
	NM_001081219
	NP_001242970; NP_005370
	NP_001074688
	維基數すう據よりどころ
檢視けんし/編輯へんしゅう人類じんるい	檢視けんし/編輯へんしゅう小しょう鼠ねずみ

MYO1A是ぜ一いち个位于人ひと类12号ごう染色せんしょく体たい上うえ的てき基もと因いん，编码一いち种隶属ぞく肌はだ凝しこり蛋白たんぱく超ちょう家族かぞく的てき蛋白たんぱく肌はだ凝しこり蛋白たんぱく-Ia（Myosin-Ia）。MYO1A是ぜ一いち种非典型てんけい的てき肌はだ凝しこり蛋白たんぱく，与あずか编码肌はだ凝しこり蛋白たんぱく-1的てきMYH1是ぜ两种不同ふどう的てき基もと因いん。MYO1A基もと因いん的てき突变可能かのう会かい导致常つね染色せんしょく体たい显性遗传性せい耳みみ聋^[5]^[6]^[7]^[8]。

参まいり见[编辑]

肌はだ凝しこり蛋白たんぱく

参考さんこう资料[编辑]

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000166866 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000025401 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ MYO1A Gene. GeneCards. [2021-05-02]. （原始げんし内容ないよう存そん档于2021-06-04）.
^ Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA. Mapping of unconventional myosins in mouse and human. Genomics. Feb 1997, 36 (3): 431–9. PMID 8884266. doi:10.1006/geno.1996.0488.
^ Donaudy F, Ferrara A, Esposito L, Hertzano R, Ben-David O, Bell RE, Melchionda S, Zelante L, Avraham KB, Gasparini P. Multiple mutations of MYO1A, a cochlear-expressed gene, in sensorineural hearing loss. Am J Hum Genet. May 2003, 72 (6): 1571–7. PMC 1180318 . PMID 12736868. doi:10.1086/375654.
^ Entrez Gene: MYO1A myosin IA. [2021-05-02]. （原始げんし内容ないよう存そん档于2009-09-22）.

这是一いち篇へん與あずか生物せいぶつ化學かがく相關そうかん的てき小しょう作品さくひん。你可以通过编辑或ある修おさむ订扩充其内容ないよう。

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000166866 - Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000025401 - Ensembl, May 2017

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] MYO1A Gene. GeneCards. [2021-05-02]. （原始げんし内容ないよう存そん档于2021-06-04）.

[pmid8884266-6] Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA. Mapping of unconventional myosins in mouse and human. Genomics. Feb 1997, 36 (3): 431–9. PMID 8884266. doi:10.1006/geno.1996.0488.

[pmid12736868-7] Donaudy F, Ferrara A, Esposito L, Hertzano R, Ben-David O, Bell RE, Melchionda S, Zelante L, Avraham KB, Gasparini P. Multiple mutations of MYO1A, a cochlear-expressed gene, in sensorineural hearing loss. Am J Hum Genet. May 2003, 72 (6): 1571–7. PMC 1180318 . PMID 12736868. doi:10.1086/375654.

[entrez-8] Entrez Gene: MYO1A myosin IA. [2021-05-02]. （原始げんし内容ないよう存そん档于2009-09-22）.

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