MYO1C

MYO1C
已やめ知的ちてき結構けっこう
PDB	直系ちょっけい同どう源みなもと搜さがせ尋ひろ: PDBe RCSB
PDBID列れつ表ひょう
	4BYF
識別しきべつ號ごう
別名べつめい	MYO1C；, MMI-beta, MMIb, NMI, myr2, myosin IC, MyoIC
外部がいぶID	OMIM：606538 MGI：106612 HomoloGene：32046 GeneCards：MYO1C
基もと因いん位置いち（人類じんるい）
染色せんしょく體たい	17號ごう染色せんしょく體たい
終止しゅうし	1,492,686 bp
基もと因いん位置いち（小しょう鼠ねずみ）
染色せんしょく體たい	小しょう鼠ねずみ11號ごう染色せんしょく體たい
終止しゅうし	75,564,736 bp
RNA表ひょう達たち模も式しき
	; ;
	查閱更さら多た表ひょう達たち數すう據よりどころ
基もと因いん本體ほんたい
分子ぶんし功こう能のう	• protein C-terminus binding; • 核かく苷酸結合けつごう; • actin binding; • signaling receptor binding; • cytoskeletal motor activity; • calmodulin binding; • ATP結合けつごう; • 血漿けっしょう蛋白たんぱく結合けつごう; • microfilament motor activity; • actin filament binding; • microtubule motor activity; • microtubule binding;
細胞さいぼう組ぐみ分ぶん	• 外そと排はい體たい; • filamentous actin; • 刷すり狀じょう緣えん; • 核かく仁ひとし; • 細胞さいぼう質しつ; • 核かく孔あな; • cell projection; • 細胞さいぼう質しつ基質きしつ; • 細胞さいぼう核かく; • 應力おうりょく纖維せんい; • stereocilium; • unconventional myosin complex; • 微ほろ絨毛じゅうもう; • basal plasma membrane; • 膜まく; • myosin I complex; • ruffle; • 脂あぶら筏いかだ模型もけい; • 細胞さいぼう膜まく; • myosin complex; • cytoplasmic vesicle; • stereocilium membrane; • lateral plasma membrane; • ruffle membrane; • 核質かくしつ; • nuclear body; • stereocilium bundle; • cytoplasmic vesicle membrane; • phagocytic vesicle;
生物せいぶつ學がく過程かてい	• Fc-gamma receptor signaling pathway involved in phagocytosis; • positive regulation of protein targeting to membrane; • positive regulation of cell migration by vascular endothelial growth factor signaling pathway; • epigenetic maintenance of chromatin in transcription-competent conformation; • positive regulation of cell migration; • 蛋白質たんぱくしつ導しるべ向むこう; • regulation of bicellular tight junction assembly; • protein transport; • protein targeting to membrane; • mRNA transport; • positive regulation of vascular endothelial growth factor signaling pathway; • positive regulation of cellular response to insulin stimulus; • positive regulation of actin filament polymerization; • transport; • vesicle transport along actin filament; • cellular response to interferon-gamma; • microtubule-based movement;
	Sources:Amigo / QuickGO
直系ちょっけい同どう源みなもと
	4641
	17913
	ENSG00000197879
	ENSMUSG00000017774
	O00159
	Q9WTI7
	NM_033375; NM_001080779; NM_001080950; NM_001363855
	NM_001080774; NM_001080775; NM_008659; NM_001370611
	NP_001074248; NP_001074419; NP_203693; NP_001350784
	NP_001074243; NP_001074244; NP_032685; NP_001357540
	維基數すう據よりどころ
檢視けんし/編輯へんしゅう人類じんるい	檢視けんし/編輯へんしゅう小しょう鼠ねずみ

MYO1C是ぜ一いち個こ位い於人類じんるい17號ごう染色せんしょく體たい上うえ的てき基もと因いん，編へん碼一いち種しゅ隸屬れいぞく肌はだ凝しこり蛋白たんぱく超ちょう家族かぞく的てき蛋白たんぱく肌はだ凝しこり蛋白たんぱく-Ic（Myosin-Ic）。MYO1C編へん碼的肌はだ凝しこり蛋白たんぱく-Ic是ぜ一種いっしゅ非ひ典型てんけい的てき肌はだ凝しこり蛋白たんぱく，與あずか編へん碼肌凝しこり蛋白たんぱく-1的てきMYH1是ぜ兩りょう種たね不同ふどう的てき基もと因いん。肌はだ凝しこり蛋白たんぱく-Ic位い於細胞さいぼう質しつ中なか，但ただし肌はだ凝しこり蛋白たんぱく-Ic的てき一種異構體位於細胞さいぼう核かく中なか，與あずかRNA聚合酶I（英語えいご：RNA polymerase I）、RNA聚合酶Ⅱ引導いんどう的てき轉てん錄ろく起おこり始はじめ有ゆう關せき^[5]^[6]^[7]。

參まいり見み

肌はだ凝しこり蛋白たんぱく

參考さんこう資料しりょう

^ ^1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000197879 - Ensembl, May 2017
^ ^2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000017774 - Ensembl, May 2017
^ Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.
^ MYO1C Gene. GeneCards. [2021-05-02]. （原始げんし內容存そん檔於2021-06-04）.
^ Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depetris D, Mattei MG, Weil D, Pujol R, Petit C. Cloning of the genes encoding two murine and human cochlear unconventional type I myosins. Genomics. Apr 1997, 40 (2): 332–41. PMID 9119401. doi:10.1006/geno.1996.4526.
^ Entrez Gene: MYO1C myosin IC. [2021-05-02]. （原始げんし內容存そん檔於2010-12-05）.

[refGRCh38Ensembl-1] 1.0 ^1.1 ^1.2 GRCh38: Ensembl release 89: ENSG00000197879 - Ensembl, May 2017

[refGRCm38Ensembl-2] 2.0 ^2.1 ^2.2 GRCm38: Ensembl release 89: ENSMUSG00000017774 - Ensembl, May 2017

[3] Human PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] Mouse PubMed Reference:. National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] MYO1C Gene. GeneCards. [2021-05-02]. （原始げんし內容存そん檔於2021-06-04）.

[pmid9119401-6] Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depetris D, Mattei MG, Weil D, Pujol R, Petit C. Cloning of the genes encoding two murine and human cochlear unconventional type I myosins. Genomics. Apr 1997, 40 (2): 332–41. PMID 9119401. doi:10.1006/geno.1996.4526.

[entrez-7] Entrez Gene: MYO1C myosin IC. [2021-05-02]. （原始げんし內容存そん檔於2010-12-05）.

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