1,3-二甲基戊胺

1,3-二甲基戊胺
臨床りんしょう資料しりょう
其他名稱めいしょう	1,3-二甲基戊胺; 1,3-DMAA; 二甲基戊胺; DMAA
给药途と径みち	鼻はな内ない喷剂（英えい语：nasal spray）、口くち服ふく
ATC碼	未み分配ぶんぱい;
藥物やくぶつ動力どうりょく學がく數かず據よりどころ
生物せいぶつ半はん衰おとろえ期き	~8.5小しょう时
识别信しん息いき
	IUPAC命名めいめい法ほう 4-Methylhexan-2-amine; ;
CAS号ごう	105-41-9
PubChem CID	7753;
ChemSpider	7467 ;
UNII	X49C572YQO;
CompTox Dashboard（英えい语：CompTox Chemicals Dashboard） (EPA)	DTXSID60861715 ;
ECHA InfoCard	100.002.997
化学かがく信しん息いき
化学かがく式しき	C7H17N
摩ま尔质量りょう	115.22 g·mol−1
3D模型もけい（JSmol（英えい语：JSmol））	交互こうご式しき图像;
	SMILES CCC(C)CC(C)N;
	InChI InChI=1S/C7H17N/c1-4-6(2)5-7(3)8/h6-7H,4-5,8H2,1-3H3 ; Key:YAHRDLICUYEDAU-UHFFFAOYSA-N ;

甲きのえ基はじめ己おのれ胺（又また称たたえ1,3-二甲基戊胺、1,3-DMAA、二甲基戊胺和わDMAA；商品しょうひん名めいForthane和わGeranamine）是ぜ一いち种由礼れい来らい公司こうし发明并研发的间接拟交感こうかん神しん经药，自じ1948年ねん以来いらい作さく为一种吸入きゅうにゅう型がた鼻はな塞ふさが缓解剂（英えい语：nasal decongestant）投なげ放ひ市し场，但ただし于1970年代ねんだい被ひ停止ていし销售。^[2]

自じ2006年ねん以来いらい，甲きのえ基はじめ己おのれ胺以许多名称めいしょう作さく为兴奋剂或ある提ひさげ高だか能のう量的りょうてき补剂广泛销售，据すえ说是因いん为它类似于老ろう鹳草中なか的てき某ぼう些化合かごう物ぶつ，但ただし因よし具有ぐゆう数すう个不良ふりょう副作用ふくさよう而受到质疑，至いたり少しょう有ゆう五个死亡与含甲基己胺的补剂有关。^[3]它被许多运动管理かんり局きょく和わ政府せいふ机つくえ构禁止きんし。即そく使つかいFDA已やめ发出几封警告けいこく信しんじ，^[4]截至2019年ねん，这种化合かごう物ぶつ仍出现于运动和わ减肥补剂中ちゅう。^[5]

参まいり见

参考さんこう文献ぶんけん

^ 1,3-Dimethylpentylamine - Compound Summary. PubChem Compound. USA: National Center for Biotechnology Information. Identification and Related Records. 26 March 2005 [27 May 2012]. （原始げんし内容ないよう存そん档于2014-03-01）.
^ Cohen, Pieter A. DMAA as a Dietary Supplement Ingredient. Archives of Internal Medicine. 9 July 2012, 172 (13): 1038–9. PMID 22566490. doi:10.1001/archinternmed.2012.1677 .
^ Singer, Natasha; Peter Lattman. F.D.A. Issues Warning on Workout Supplement. New York Times. April 16, 2013 [April 16, 2013]. （原始げんし内容ないよう存そん档于2019-01-03）.
^ FDA, Center for Food Safety and Applied. Products & Ingredients - DMAA in Products Marketed as Dietary Supplements. FDA. May 2019 [2022-02-22]. （原始げんし内容ないよう存そん档于2019-04-23）（英えい语）.
^ Cohen, Pieter A.; Wen, Anita; Gerona, Roy. Prohibited Stimulants in Dietary Supplements After Enforcement Action by the US Food and Drug Administration. JAMA Internal Medicine. 1 December 2018, 178 (12): 1721–1723. PMC 6583602 . PMID 30422217. doi:10.1001/jamainternmed.2018.4846.

外部がいぶ链接

Stimulant Potentially Dangerous to Health, FDA Warns. U.S. Food and Drug Administration. April 11, 2013 [2022-02-22]. （原始げんし内容ないよう存そん档于2014-02-01）.
Bussel, Igor I; Pavlov Jr, Andrey A. DMAA: Efficacious but is it Safe?. Science Based Medicine Blog. June 7, 2013 [2022-02-22]. （原始げんし内容ないよう存そん档于2013-06-09）.

[1] 1,3-Dimethylpentylamine - Compound Summary. PubChem Compound. USA: National Center for Biotechnology Information. Identification and Related Records. 26 March 2005 [27 May 2012]. （原始げんし内容ないよう存そん档于2014-03-01）.

[2] Cohen, Pieter A. DMAA as a Dietary Supplement Ingredient. Archives of Internal Medicine. 9 July 2012, 172 (13): 1038–9. PMID 22566490. doi:10.1001/archinternmed.2012.1677 .

[nyt-fda-3] Singer, Natasha; Peter Lattman. F.D.A. Issues Warning on Workout Supplement. New York Times. April 16, 2013 [April 16, 2013]. （原始げんし内容ないよう存そん档于2019-01-03）.

[4] FDA, Center for Food Safety and Applied. Products & Ingredients - DMAA in Products Marketed as Dietary Supplements. FDA. May 2019 [2022-02-22]. （原始げんし内容ないよう存そん档于2019-04-23）（英えい语）.

[5] Cohen, Pieter A.; Wen, Anita; Gerona, Roy. Prohibited Stimulants in Dietary Supplements After Enforcement Action by the US Food and Drug Administration. JAMA Internal Medicine. 1 December 2018, 178 (12): 1721–1723. PMC 6583602 . PMID 30422217. doi:10.1001/jamainternmed.2018.4846.

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